Rose Bengal

Name: Rose Bengal

CAS Registry Number: 632-69-9

CA Index Name: Spiro[isobenzofuran-1(3H),90-[9H] xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-, sodium salt (1:2)

Other Names: C.I. 45440; C.I. Acid Red 94; Bengal Rose B sodium salt; Fluorescein, 4,5,6,7-tetrachloro-2',4',5',7'-tetraiodo-, disodium salt; Spiro[isobenzofur-an-1(3H),90-[9H]xanthen]-3-one, 4,5,6,7-tetrachloro-3',6'-dihydroxy-2',4',5',7'-tetraiodo-, disodium salt; 2',4',5',7'-Tetraiodo-3,4,5,6-tetrachlorofluorescein disodium salt; 3',4',5',6'-Tetrachloro-2,4,5,7-tetraiodofluores-cein disodium salt; Japan Red 105-1; Rose Bengal Extra; Rose Bengal disodium salt; Rose Bengal extra; Rose Bengal sodium; Rose Bengal sodium salt; Sodium tetraiodotetrachlorofluorescein

Merck Index Number: 8262

Chemical / Dye Class: Xanthene

Molecular Formula: C₂₀H₂Cl₄I₄Na₂O₅

Molecular Weight: 1017.64

Physical Form: Red-brown powder

Solubility: Soluble in water, ethanol

Melting Point: > 200 °C

pK_a: 3.9, 4.7

Absorption (λ_max): 548 nm

Emission (λ_max): 567 nm

Synthesis: Synthetic methods

Staining Applications: Bacteria; apoptotic cells; bacterial spores; proteins; hairs

Biological Applications: Apoptosis assay; diagnosis of diseases related to amyloid accumulation; controlling plant diseases; identifying fungi; treating skin, mouth, digestive tract, urinary tract, reproductive tract, respiratory tract, circulatory system, head and neck, endocrine system, lymphoreticular system, rhinitis, asthma, urticaria, atopic dermatitis, anaphylactic shock; photodynamic therapy; pesticides; insecticides; fungicides

Industrial Applications: Organic photodetectors; memory devices; solar cells; semiconductor film; imaging method; optical filters; antireflection films; as polymerization photoinitiators; recording materials; thermoplastics; cements; photographic materials

Safety / Toxicity: Genotoxicity; microbial toxicity

Certification / Approval: Certified by Biological Stain Commission (BSC)

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