Hoechst 33342
Name: Hoechst 33342
CAS Registry Number: 23491-52-3
CA Index Name: 2,5'-Bi-1H-benzimidazole, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-,hydrochloride (1:3)
Other Names: 2,5'-Bibenzimidazole, 2'-(p-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-; 2'-(4-Ethoxyphenyl)-5- (4-methyl- 1-piperazinyl)-2,5'-bi-1H-benzimidazole; 2-[2-(4-Ethoxyphenyl)-6-benzimidazolyl]-6-(1-methyl-4-piperazinyl)benzimidazole; Bisbenzimide; HOE 33342; Ho 342; Hoechst 33342; NSC 334072
Merck Index Number: Not listed
Chemical / Dye Class: Benzimidazole
Molecular Formula: C27H31Cl3N6O
Molecular Weight: 561.93
Physical Form: Yellow to green powder
Solubility: Soluble in water, N,N-dimethyl formamide
Melting Point: > 300 °C
Boiling Point: 725.9 ± 70.0 °C, pressure: 760 Torr
pKa: 11.08 ± 0.69, most acidic, temperature: 25 °C; 7.66 ± 0.42, most basic, temperature: 25 °C
Absorption (λmax): 350 nm
Emission (λmax): 461 nm
Synthesis: Synthetic methods
Staining Applications: Nucleic acids; cells; neurons; endothelial cells; inflammatory cells; cancer stem cells; animal mammary gland stem cells; hematopoietic stem cells; hepatocytes stem cells; human tumor cell; SV40 human corneal epithelial cell; microorganisms; nuclei; parasites; chromosomes; sperms
Biological Applications: Detecting abnormal gametes, apoptosis, human papilloma virus (HPV), single nucleotide polymorphism (SNP), mitochondrial membrane potential change, polynucleotides, proteins, peptides; nucleic acid amplification; nucleic acid quantification; nucleic acid sequencing; treating of cancer, Alzheimers disease, multiple sclerosis, epilepsy
Industrial Applications: Not reported
Safety / Toxicity: Carcinogenicity; cytotoxicity; DNA damage; genotoxicity; metabolic toxicity; mutagenicity; neurotoxicity; radiotoxicity; reproductive toxicity
Fundamentals of Bioorganic Chemistry The texlbook is based on modern organic chemistry and considers the structure and chemical transformations of organic compounds, especially those that ...
Метод молекулярных орбит и реакционная способность органических молекул Монография посвящена применению методов квантовой химии для количественной ...
Allen’s commercial organic analysis Allen’s commercial organic analysis; a treatise on the properties, modes of assaying, and proximate analytical examination of the various organic ...
Синтетический каучук В книге изложены результаты обширных исследований в области синтеза различных ...