DAPI
Name: DAPI
CAS Registry Number: 28718-90-3
CA Index Name: 1H-Indole-6-carboximidamide, 2-[4-(aminoiminomethyl)phenyl]-, dihydrochloride
Other Names: Indole-6-carboxamidine, 2-(p-amidino-phenyl)-, dihydrochloride; 4',6-Diamidino-2-phenylin-dole dihydrochloride; 6-Amidino-2-(4-amidinophenyl) indole dihydrochloride; DAPI
Merck Index Number: Not listed
Chemical / Dye Class: Indole
Molecular Formula: C16H17Cl2N5
Molecular Weight: 350.25
Physical Form: Yellow powder
Solubility: Soluble in water, N,N-dimethylformamide
Melting Point: > 200 °C
Absorption (λmax): 358 nm, 342 nm
Emission (λmax): 461 nm, 450 nm
Synthesis: Synthetic methods
Staining Applications: Nucleic acids; bacteria; cells; chromosomes; microorganisms; neuron-specific nuclear protein NeuN; polynucleotide; proteins
Biological Applications: Nuclear apoptosis assay; targeting drug to cerebral neuron; treating amyloidosis, neurodegenerative diseases, Alzheimer’s disease, Down’s syndrome, type II diabetes; monitoring bioaerosols
Industrial Applications: Not reported
Safety / Toxicity: No data available
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