Phloxine B
Name: Phloxine B
CAS Registry Number: 18472-87-2
CA Index Name: Spiro[isobenzofuran-1(3H),9'-[9H] xanthen]-3-one, 2',4',5',7'-tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-, sodium salt (1:2)
Other Names: Fluorescein, 2',4',5',7'-tetrabromo-4,5,6, 7-tetrachloro-, disodium salt; Phloxin B; Spiro[isobenzo-furan-1(3H),9'-[9H]xanthen]-3-one, 2',4',5',7'-tetrabro-mo-4,5,6,7-tetrachloro-3',6'-dihydroxy-, disodium salt; 11969 Red; 3427 Veri Pur Pink; Acid Red 92; Aizen Acid Phloxine PB; C.I. 45410; C.I. Acid Red 92; Cyanosin; Cyanosin (acid dye); Cyanosin B; Cyanosine; D and C Red No. 28; D&C Red 28; D&C Red 28-308267; D&C Red No. 28; D&C Red No. 28-15347; D&C Red No. 2838015; Daiwa Red 104WB; Daiwa Red 45; Disodium 9-(3' ,4',5',6'-tetrachloro-o-carboxyphenyl)-6-hydroxy-6-hydroxy-2,4,5,7-tetrabromo-3-isoxanthone; Eosin blue; Eosin bluish; Eosine blue; Eosine bluish; Food Red 104; Food Red No. 104; Japan Red 104; Japan Red 104-1; Japan Red No. 104-1; Orient Water Pink 2; Phlox-ine B; Phloxine B 38015; Phloxine P; Phyloxine B; Red 104; Red No. 104; Red No. 104-1; Triacid Floxine 2G; Water Pink 2
Merck Index Number: Not listed
Chemical / Dye Class: Xanthene
Molecular Formula: C20H2Br4Cl4Na2O5
Molecular Weight: 829.66
Physical Form: Red to brown crystals
Solubility: Soluble in water, ethylene glycol; slightly soluble in ethanol, methanol
Melting Point: > 250 °C
pH Range: 1.1-3.3; 3.4-5.0
Color Change at pH: Colorless (1.1) to purple (3.3); colorless (3.4) to yellow (5.0)
Absorption (λmax): 548 nm, 510 nm
Synthesis: Synthetic methods
Staining Applications: Albumin; aluminum; bacteria; candies; drinks; dental plaque; lymph node; proteins; peptides; carious tissue; teeth; sunscreen; eyebrows; eyelashes; eye shadow; fingerprint powders; lipsticks; lips; nails; skin; hairs; keratin fibers
Biological Applications: Detecting proteins; treating microbial infection, parasitic infection, skin, mouth, digestive tract, urinary tract, reproductive tract, respiratory tract, circulatory system, head, neck, endocrine system, lymphoreticular system, cystic fibrosis, disseminated bronchectasis, pulmonary infections, chronic pancreatitis, male infertility, long QT syndrome, protozoan infections, yeast infection, fungal infections; antimicrobial agent; insecticides; herbicides
Industrial Applications: Color filter; liquid-crystal displays; solar cells; optical waveguides; electro-chromic displays; photoresists; recording materials; photographic materials; inks; toner; highlighters; paints; adhesives; petroleum markers; cleansing products
Safety / Toxicity: Acute toxicity; chronic toxicity; cytotoxicity; genotoxicity; insect toxicity; microbial toxicity; mutagenicity; oral toxicity; photodynamic toxicity; phototoxicity; teratogenicity; yeast toxicity
Certification / Approval: Certified by Biological Stain Commission (BSC)
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