BAPTA
Name: BAPTA
CAS Registry Number: 85233-19-8
CA Index Name: Glycine, N,N-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-
Other Names: 1,2-Bis(2-aminophenoxy)ethane-N,N',N', N-tetraacetic acid; 1,2-Bis(o-aminophenoxy)ethane-N,N,N',N' -tetraacetic acid; Ethylenedioxybis(o-phenylenenitri-lo)tetraacetic acid; 2,2 -(Ethylenedioxy)dianiline-N,N,N,N'-tetraacetic acid; BAPTA
Merck Index Number: 957
Chemical / Dye Class: Aromatic
Molecular Formula: C22H24N2O10
Molecular Weight: 476.43
Physical Form: Beige powder
Solubility: Soluble in dimethyl sulfoxide
Melting Point: 149-159 °C
Boiling Point: 766.6 ± 60.0 °C, pressure: 760 Torr
pKa: 1.40 ± 0.10, most acidic, temperature: 25 °C; 5.96 ± 0.38, most basic, temperature 25 °C
Absorption (λmax): 209 nm, 254 nm, 203 nm, 274 nm
Emission (λmax): 363 nm
Synthesis: Synthetic methods
Staining Applications: Calcium ions; zinc ions; bone; proteins
Biological Applications: Calcium indicators; zinc indicators; treating acute cell death, cerebral infarction, myocardial infarction, hepatonecrosis, kidney ischemic necrosis, necrotizing pancreatitis, amyloidosis, atherosclerosis, diseases characterized by calcification and/or plaque formation, osteoporosis, Paget’s disease, heterotropic ossification, hypercalcemia, cancer, inflammation, diabetes mellitus, epilepsy, epithelial disorders, glaucoma, HIV-associated conditions, respiratory disorders, streptococcal infection, viral diseases
Industrial Applications: Inks
Safety / Toxicity: Carcinogenicity; cytotoxicity; excitotoxicity; hydrogen peroxide toxicity; neurotoxicity
Micro-chemistry of Poisons Micro-chemistry of poisons: including their physiological, pathological, and legal relations; with an appendix on the detection and microscopic ...
Fundamentals of Bioorganic Chemistry The texlbook is based on modern organic chemistry and considers the structure and chemical transformations of organic compounds, especially those that ...