NBD C6-Ceramide
Name: NBD C6-Ceramide
CAS Registry Number: 86701-10-2
CA Index Name: Hexanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-6-[(7-nitro-2,1,3-benzox-adiazol-4-yl)amino]-
Other Names: Hexanamide, N-[2-hydroxy-1-(hydroxy-methyl)-3-heptadecenyl]-6-[(7-nitro-2,1,3-benzoxadia-zol-4-yl)amino]-; Hexanamide, N-[2-hydroxy-1-(hydro-xymethyl)-3-heptadecenyl]-6-[(7-nitro-4-benzofurazanyl) amino]-; 2,1,3-Benzoxadiazole, hexanamide derivative; N-(NBD-aminohexanoyl)sphingosine; NBD C6-ceramide
Merck Index Number: Not listed
Chemical / Dye Class: Benzoxadiazole
Molecular Formula: C30H49N5O6
Molecular Weight: 575.74
Physical Form: Orange powder
Solubility: Soluble in chloroform, methanol, dimethyl sulfoxide
Melting Point: > 200 °C
pKa: 13.54 ± 0.20, most acidic, temperature: 25 °C; —0.78 ± 0.70, most basic, temperature: 25 °C
Absorption (λmax): 466 nm
Emission (λmax): 536 nm
Synthesis: Synthetic methods
Staining Applications: Golgi apparatus; lipids; lipopolysaccharides; lipoproteins; sphingolipids; vacuoles
Biological Applications: Analyzing lipoproteins; lipid metabolism; sphingolipid metabolism; sphingolipid transport; drug screening assay; inositol phosphatidyl ceramide (IPC) synthase assay; sphingomyelinase activity assay; treating fungal infections44
Industrial Applications: Semiconductors
Safety / Toxicity: Fungal toxicity; tumor necrosis
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