DiOC2(3)
Name: DiOC2(3)
CAS Registry Number: 905-96-4
CA Index Name: Benzoxazolium, 3-ethyl-2-[3-(3-ethyl-2(3H)-benzoxazolylidene)-1-propen-1-yl]-, iodide (1:1)
Other Names: 3-Ethyl-2-[3-(3-ethyl-2-benzoxazoliny-lidene)propenyl]benzoxazolium iodide; Benzoxazolium, 3-ethyl-2-[3-(3-ethyl-2(3H)-benzoxazolylidene)-1-pro-penyl]-, iodide; Benzoxazolium, 3-ethyl-2-[3-(3-ethyl-2-benzoxazolinylidene)propenyl]-, iodide; 3,3'-Diethyl-2,20-oxacarbocyanine iodide; 3,3'-Diethyloxacarbocya-nine iodide; 3-Ethyl-2-[3-ethyl-2(3H)-benzoxazolyli-dene)-1-propenyl]benzoxazolium iodide); DOC; DOC (dye); DOC iodide; DOCI; DiOC2; DiOC2(3); G 1745; NK 85
Merck Index Number: Not listed
Chemical / Dye Class: Cyanine
Molecular Formula: C21H21IN2O2
Molecular Weight: 460.31
Physical Form: Dark red crystals or powder
Solubility: Soluble in methanol, dimethyl sulfoxide
Melting Point: 278 °C (decompose); 210 °C (decompose) (impure)
Absorption (λmax): 482 nm
Emission (λmax): 497 nm
Synthesis: Synthetic methods
Staining Applications: Hepatocytes; P-glycoprotein; malaria infected cells; nucleic acids; sperms; hairs
Biological Applications: Measuring membrane potential; detecting prostate cancer, nucleic acid hybridization, polynucleotides; treating acute myelogenous leukemia, metastatic breast cancer, cancers expressing P-glycoprotein
Industrial Applications: Dye laser; displays; recording materials; light emitting diode lens; thin films; photographic materials; nonlinear optical materials; solar panels
Safety / Toxicity: Carcinogenicity
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