Monobromobimane (mBBr)
Name: Monobromobimane (mBBr)
CAS Registry Number: 71418-44-5
CA Index Name: 1H,7H-Pyrazolo[1,2-a]pyrazole-1,7-dione, 3-(bromomethyl)-2,5,6-trimethyl-
Other Names: Bromobimane; Monobromobimane; NSC 608544; Thiolyte MB
Merck Index Number: Not listed
Chemical / Dye Class: Pyrazole
Molecular Formula: C10H11BrN2O2
Molecular Weight: 271.11
Physical Form: Yellow powder
Solubility: Soluble in acetonitrile, dichloromethane, methanol, N,N-dimethyl formamide, dimethyl sulfoxide
Melting Point: 160-161 °C, 152-154 °C
Boiling Point: 327.8 ± 44.0 °C, pressure: 760 Torr
pKa: —3.57 ± 0.70, most basic, temperature: 25 °C
Absorption (λmax): 398 nm
Emission (λmax): 490 nm
Synthesis: Synthetic method
Staining Applications: Cystine; cysteine; cysteine; cysteine-111; captopril; erythrocytes; mutants; neurons; nucleic acids; proteins; peptides; sulfhydryls
Biological Applications: Glutathione S-transferase substrates; detecting glutathione S-transferase, thiols, sulfite, homocysteine, mycothiol, sulfur compounds; thiol-reactive probes
Industrial Applications: Photographic materials
Safety / Toxicity: Hepatotoxicity; mutagenicity; reproductive toxicity
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