Ethidium Homodimer-1 (EthD-1)
Name: Ethidium Homodimer-1 (EthD-1)
CAS Registry Number: 61926-22-5
CA Index Name: Phenanthridinium, 5,5'-[1,2-ethane-diylbis(imino-3,1-propanediyl)]bis[3,8-diamino-6-phenyl-, chloride, hydrochloride (1:2:2)
Other Names: Phenanthridinium, 5,5'-[1,2-ethanediyl-bis(imino-3,1-propanediyl)]bis[3,8-diamino-6-phenyl-, dichloride, dihydrochloride; 5,5'-(4,7-Diazadecamethy-lene)bis(3,8-diamino-6-phenylphenanthridinium) dichloride dihydrochloride; EB2; ETDI; EthD 1; EtDi; Ethidium dimer; Ethidium homodimer; Ethidium homodimer 1
Merck Index Number: Not listed
Chemical / Dye Class: Phenanthridine
Molecular Formula: C46H50Cl4N8
Molecular Weight: 856.77
Physical Form: Red powder
Solubility: Soluble in water, N,N-dimethylformamide, dimethyl sulfoxide
Melting Point: 275 °C
Absorption (λmax): 528 nm
Emission (λmax): 617 nm
Synthesis: Synthetic methods
Staining Applications: Nucleic acids; cells; leukocytes; nuclei; megakaryocytes; microorganisms; nucleated red blood cells; sperms; Schwann cells (SCs) in whole nerves
Biological Applications: Nucleic acid hybridization; detecting nucleic acids, cells, retinoblastoma susceptibility gene protein (pRB), enzymes, PCR products, viral infection; nucleic acid amplification; nucleic acid fragment sizing; counting embryoblasts; treating cancer
Industrial Applications: For authentification
Safety / Toxicity: Cytotoxicity; gastric toxicity; neurotoxicity; retinal toxicity
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