9-Amino-6-chloro-2-methoxyacridine (ACMA)
Name: 9-Amino-6-chloro-2-methoxyacridine (ACMA)
CAS Registry Number: 3548-09-2
CA Index Name: 9-Acridinamine, 6-chloro-2-methoxy-
Other Names: Acridine, 9-amino-6-chloro-2-methoxy-; 2-Methoxy-6-chloro-9-aminoacridine; 3-Chloro-7-meth-oxy-9-aminoacridine; 6-Chloro-9-amino-2-methoxyacri-dine; 9-Amino-3-chloro-7-methoxyacridine; 9-Amino-6-chloro-2-methoxyacridine; G 185; NSC 15300
Merck Index Number: Not listed
Chemical / Dye Class: Acridine
Molecular Formula: C14H11ClN2O
Molecular Weight: 258.70
Physical Form: Yellow crystals
Solubility: Soluble in methanol, N,N-dimethylformamide, dimethylsulfoxide
Melting Point: 272-274 °C
Boiling Point: 475.1 ± 35.0 °C, pressure: 760 Torr
pKa: 8.6
Absorption (λmax): 412 nm
Emission (λmax): 471 nm
Synthesis: Synthetic methods
Staining Applications: Nucleic acids; cells; chromosomes; microorganisms
Biological Applications: Antimalarial; bactericidal; detection of cancer cells, nucleic acids; treating malformed proteins causing neurodegenerative disease
Industrial Applications: Not reported
Safety / Toxicity: Genotoxicity; mutagenicity
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